Thermo Fisher Scientific Phospho-Rb (Ser788) Recombinant Rabbit Monoclonal Antibody (6H13L22)
Rb 단백질의 Ser788 인산화 형태를 검출하는 고특이성 재조합 토끼 단일클론 항체. Western blot 및 면역세포염색에 적합. 높은 로트 간 일관성과 민감도 제공. 인간 및 다양한 종에 반응 예측. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 6H13L22 |
| Immunogen | Peptide corresponding to Human RB1 (aa 784–791) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2632993 |
Product Specific Information
This antibody is predicted to react with Monkey, Rabbit, Bovine, and Pig.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal candidates for production.
Advantages include:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
Rb is a tumor suppressor nuclear phosphoprotein that binds to DNA. It is phosphorylated on serine and threonine residues and forms complexes with SV40 large T antigen, adenovirus E1A, and HPV-16 E proteins.
Loss of Rb function leads to uncontrolled cell growth. Aberrations in the RB gene are associated with cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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