Thermo Fisher Scientific RLBP1 Monoclonal Antibody (OTI5G2), TrueMAB
RLBP1 단백질을 인식하는 Mouse monoclonal antibody로 Western blot에 적합. Human 시료 반응성. 동결건조 형태로 제공되며, PBS 버퍼에 8% trehalose 포함. 시각 재생 경로 연구 및 RPE 세포 마커 분석에 유용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5G2 |
| Immunogen | Full length human recombinant protein of human RLBP1 produced in HEK293 cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Cellular retinaldehyde-binding protein (CRALBP) plays a crucial role in regenerating 11-cis-retinal for use in visual pigments such as opsin and rhodopsin.
After photoisomerization, 11-cis-retinal is converted to all-trans-retinal, then to all-trans-retinol, which diffuses into the retinal pigment epithelium (RPE) to be reconverted into 11-cis-retinol and subsequently oxidized to 11-cis-retinal by CRALBP.
Mutations in CRALBP function are associated with visual disorders such as Bothnia dystrophy, retinitis punctata albescens, retinitis pigmentosa, and Newfoundland rod-cone dystrophy.
CRALBP is a known marker for RPE and Müller glial cells of the retina.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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