Thermo Fisher Scientific RLBP1 Monoclonal Antibody (OTI5G2), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

Cellular retinaldehyde-binding protein (CRALBP) plays a crucial role in regenerating 11-cis-retinal for use in visual pigments such as opsin and rhodopsin.
After photoisomerization, 11-cis-retinal is converted to all-trans-retinal, then to all-trans-retinol, which diffuses into the retinal pigment epithelium (RPE) to be reconverted into 11-cis-retinol and subsequently oxidized to 11-cis-retinal by CRALBP.
Mutations in CRALBP function are associated with visual disorders such as Bothnia dystrophy, retinitis punctata albescens, retinitis pigmentosa, and Newfoundland rod-cone dystrophy.
CRALBP is a known marker for RPE and Müller glial cells of the retina.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.