Thermo Fisher Scientific GDAP1L1 Monoclonal Antibody (OTI1G5), TrueMAB
인간 GDAP1L1 단백질을 인식하는 Mouse IgG1 단일클론 항체로, WB, ICC/IF, Flow Cytometry에 적합. 동결건조 형태로 제공되며, 고순도의 affinity chromatography 정제. 연구용으로 Charcot-Marie-Tooth 관련 연구에 활용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G5 |
| Immunogen | Full-length human recombinant protein of human GDAP1L1 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using carrier-free antibody, perform desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The ganglioside GD3 synthase induces neurite sprouting and cell differentiation when transfected into mouse neuroblastoma Neuro2a cells. After differentiation, several genes are upregulated, including ganglioside-induced differentiation-associated protein 1 (Gdap1).
A similar gene in humans, GDAP1L1, is associated with Charcot-Marie-Tooth type 4A disease. The protein encoded by this gene shares sequence similarity with human GDAP1. Multiple transcript variants, including noncoding forms, have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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