Thermo Fisher Scientific RLBP1 Monoclonal Antibody (OTI1F5), TrueMAB
인간 RLBP1 단백질을 인식하는 단클론 항체로, Western blot에 적합합니다. TrueMAB 형식의 Mouse IgG1 항체이며, 고순도 친화 크로마토그래피로 정제되었습니다. 시각 관련 단백질 연구 및 RPE 세포 마커 분석에 활용됩니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F5 |
| Immunogen | Full-length human recombinant RLBP1 protein produced in HEK293 cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882) to obtain a carrier-free antibody.
Target Information
Cellular retinaldehyde-binding protein (CRALBP) is essential for regenerating 11-cis-retinal used in rod visual pigments such as opsin and rhodopsin.
After photoisomerization, all-trans-retinal is converted to all-trans-retinol, which diffuses into the retinal pigment epithelium (RPE) for conversion back to 11-cis-retinol and oxidation to 11-cis-retinal, both catalyzed by CRALBP.
Mutations in CRALBP are associated with visual diseases such as Bothnia dystrophy, retinitis punctata albescens, retinitis pigmentosa, and Newfoundland rod-cone dystrophy.
CRALBP serves as a marker for RPE and Müller glial cells in the retina.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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