Thermo Fisher Scientific Caspase 7 Polyclonal Antibody
Caspase 7 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P) 분석에 사용 가능. Human, Mouse, Rat 시료에 반응하며, 액상 형태로 1 mg/mL 농도. 세포사멸 관련 연구에 적합한 고품질 항체.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human Caspase 7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2691977 |
Product Specific Information
Predicted to react with Human, Mouse, and Rat samples.
Target Information
Caspase 7 is part of a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the inflammatory caspases, apoptotic caspases are involved in programmed cell death. Caspase 7 functions as an executioner caspase, activated by initiator caspases to cleave cellular substrates leading to apoptosis. It shares homology with caspases 1 and 3, as well as C. elegans CED-3. Alternative splicing of Caspase-7 mRNA produces three distinct isoforms. Caspase-7 activity can be inhibited by XIAP expression. Diseases associated with CASP7 include Type 1 Diabetes Mellitus 17 and Aleutian Mink Disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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