Thermo Fisher Scientific ASIP Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000

Product Specifications

Target Information

In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may:

1. Affect the quality of hair pigmentation
2. Act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone
3. Play a role in neuroendocrine aspects of melanocortin action
4. Have a functional role in regulating lipid metabolism in adipocytes

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.