Thermo Fisher Scientific ILP-2 Polyclonal Antibody
Rabbit Polyclonal ILP-2 항체로 Western blot에 적합하며 인간 ILP-2 유래 합성 펩타이드로 면역화됨. Mouse 및 Rat 시료에도 반응 예측. 액상 형태, 1 mg/mL 농도, -20°C 보관. 세포사멸 관련 연구용으로 최적화된 항체.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human ILP-2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2691782 |
Product Specific Information
Predicted to react with Mouse and Rat samples.
Target Information
Apoptosis, or programmed cell death, is related to many diseases such as cancer. Apoptosis is triggered by various stimuli including members of the TNF family and inhibited by IAP (inhibitor of apoptosis) proteins. IAP proteins form a conserved gene family including IAP, XIAP/ILP-1/MIHA, and Livin/KIAP that bind and inhibit specific proteases.
A novel member, ILP-2 (IAP-like protein-2), was identified with high homology to ILP-1 but encoded by a distinct gene expressed only in testis of normal human tissues. Unlike ILP-1, ILP-2 does not inhibit Fas or TNF-induced apoptosis but strongly inhibits apoptosis induced by Bax overexpression or coexpression of caspase-9 with Apaf-1. ILP-2 interacts with processed caspase-9, suggesting it is a novel IAP family member with restricted specificity for caspase-9.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: PA5-67914_ILP-2_Q96P09-1_Rabbit.svg, PA5-67914_ILP-2_Q96P09-1_Rabbit_PDP.jpeg)
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