
Thermo Fisher Scientific Cytochrome C Monoclonal Antibody (7H8.2C12)
다양한 종에서 반응하는 Cytochrome C 단일클론 항체로, Western blot, IHC, ICC 등 다양한 응용에 적합합니다. 마우스 IgG2b, kappa 아이소타입이며, 액상 형태로 제공됩니다. 세포 사멸 연구 및 미토콘드리아 단백질 분석에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 13 publications |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | – | View 1 publication |
| Immunocytochemistry (ICC/IF) | – | View 2 publications |
| Immunoprecipitation (IP) | – | View 2 publications |
| Miscellaneous PubMed (Misc) | – | View 4 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Fruit fly, Horse, Human, Mouse, Rabbit, Rat, Xenopus |
| Published Species | Chicken, Fish, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 7H8.2C12 |
| Immunogen | Equine Cytochrome c |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2533142 |
Target Information
Cytochrome C is an electron-transporting protein located in the mitochondrial intermembrane space, playing a critical role in oxidative phosphorylation and ATP production. Its release into the cytosol is triggered by apoptotic stimuli, where it binds to apoptotic protease activating factor, leading to activation of initiator procaspase 9 and subsequently caspase 3, a key effector of apoptosis.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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