Thermo Fisher Scientific ZO-1 Monoclonal Antibody (ZO1-1A12), Alexa Fluor 594
ZO-1 단백질을 검출하기 위한 Alexa Fluor 594 결합 단클론 항체로, WB, IHC, ICC/IF, ELISA 등 다양한 응용에 적합합니다. 인간 및 개에서 반응하며, 고순도 Protein A 정제. 590/618 nm 형광 특성으로 세포접합 연구에 유용.
- 카탈로그번호
- 339194
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific ZO-1 Monoclonal Antibody (ZO1-1A12), Alexa Fluor 594
Thermo Fisher Scientific ZO-1 Monoclonal Antibody (ZO1-1A12), Alexa Fluor 594
Applications 및 Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | View 1 publication |
| Immunohistochemistry (IHC) | – | View 13 publications |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | – | View 2 publications |
| Immunocytochemistry (ICC/IF) | 1–10 µg/mL | View 15 publications |
| ELISA | 0.1–1.0 µg/mL | – |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human |
| Published Species | Chicken, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ZO1-1A12 |
| Immunogen | Human recombinant ZO-1 fusion protein encompassing amino acids 334–634 |
| Conjugate | Alexa Fluor™ 594 |
| Excitation / Emission Max | 590 / 618 nm |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 4.0 mg/mL BSA |
| Contains | 0.1% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2532188 |
Additional Formats
- Unconjugated (Cat. No. 33-9100)
- Alexa Fluor 488 (Cat. No. 339188)
- Alexa Fluor 555 (Cat. No. MA3-39100-A555)
- Alexa Fluor 647 (Cat. No. MA3-39100-A647)
- FITC (Cat. No. 33-9111)
- Custom conjugation available upon request
Target Information
ZO-1 forms complexes with ZO-2 or ZO-3 and associates with claudin, occludin, and F-actin at tight junction strands. These complexes link the actin cytoskeleton to tight junctions.
ZO-1 expression is reduced in many breast cancer cell lines. ZO-2 and ZO-3 are ubiquitously expressed in epithelial junctions, while ZO-1 is also found in cardiac myocytes.
ZO-1 may play a role in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified.
Diseases associated with ZO-1 dysfunction include Celiac Disease and Congenital Nephrotic Syndrome.
For Research Use Only.
Not for use in diagnostic procedures or resale without authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.