Thermo Fisher Scientific ZRANB1 Monoclonal Antibody (OTI2A10), TrueMAB
ZRANB1 단백질을 표적으로 하는 마우스 단클론 항체로, Western blot에 적합합니다. 인간, 마우스, 랫트 반응성이 있으며, 무보존제 상태로 동결건조 형태로 제공됩니다. Wnt 신호 경로 연구 및 단백질 탈유비퀴틴화 기전 분석에 활용 가능합니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 208–296 of human ZRANB1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional round of desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
ZRANB1 is a positive regulator of the Wnt signaling pathway that specifically cleaves Lys-63–linked ubiquitin chains. It acts by deubiquitinating the APC protein, a negative regulator of Wnt-mediated transcription, and may also modulate TNF-alpha signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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