Thermo Fisher Scientific SPAG5 Polyclonal Antibody
SPAG5 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화되어 있습니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 버퍼에 0.02% sodium azide가 포함되어 있습니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Full length recombinant protein to MAP126 (SPAG5, UniProt ID: Q96R06-1, antigen range: 1–1193, antigen length: 1193) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2194786 |
Target Information
SPAG5 (sperm associated antigen 5), also known as MAP126, hMAP126, DEEPEST, or Astrin, is a 1,193 amino acid protein expressed highly in testis and at lower levels in liver, placenta, pancreas, colon, and thymus. It localizes to spindle poles during prophase and throughout the spindle during metaphase and anaphase. SPAG5 is essential for proper spindle formation and regulation of mitotic spindles, playing roles in sister chromatid cohesion and chromosome integrity. It forms a homodimer with aster-like structures and may be phosphorylated by ATR or ATM upon DNA damage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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