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Thermo Fisher Scientific LXR alpha Polyclonal Antibody
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LXRα 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot에 적합합니다. 인간, 생쥐, 비인간 영장류, 돼지에 반응하며 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 4°C 보관, 인간 간 조직을 양성 대조군으로 권장합니다.
- 카탈로그번호
- PA116824
- 판매단위
- pk
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마지막 업데이트 2025. 08. 05. 오후 02:47
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Thermo Fisher Scientific PA116824 LXR alpha Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
689,200원VAT 포함 758,120원
Thermo Fisher Scientific · Thermo Fisher Scientific LXR alpha Polyclonal Antibody
Applications
- Western Blot (WB): 0.5–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Pig |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to an internal portion of human LXR protein (residues 50–150) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.04 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Wet ice |
| RRID | AB_568610 |
Product Specific Information
- Target sequence shows 92% homology with rat and mouse, and 90% with chicken.
- Suggested positive control: Human liver lysate or human liver protein.
Target Information
NR1H3 (LXR-alpha, oxysterols receptor) is a nuclear receptor involved in ligand-dependent transcriptional activation. It interacts with RXR to mediate retinoid responses through LXREs (DR4-type response elements). NR1H3 regulates cholesterol homeostasis by controlling cholesterol uptake via MYLIP-dependent ubiquitination of LDLR, VLDLR, and LRP8, and cooperates with RORA in liver metabolism gene regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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