Thermo Fisher Scientific GABRB3 Monoclonal Antibody (N87/25), PE
GABRB3 단클론 항체 (N87/25), PE 형광표지 제품으로 인간, 마우스, 랫트 반응성. WB, IHC, ICC/IF 등 다양한 분석에 사용 가능. 단백질 G 정제, 1 mg/mL 농도. 4°C 보관, 연구용 전용.
- 카탈로그번호
- MA545468
- 판매단위
- pk
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Thermo Fisher Scientific GABRB3 Monoclonal Antibody (N87/25), PE
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Antibody Microarray (AM) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N87/25 |
| Immunogen | Fusion protein amino acids 370–433 of mouse GABA-A-R-Beta 3 |
| Conjugate | PE |
| Excitation/Emission Max | 565/576 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931922 |
Additional Formats
- Unconjugated (MA5-27698)
- APC (MA5-45465)
- FITC (MA5-45466)
- PerCP (MA5-45467)
- Request custom conjugation
Product Specific Information
1 µg/mL of MA5-45468 was sufficient for detection of Beta 3 GABA receptor in 10 µg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
Detects approximately 55 kDa. No cross-reactivity against GABA-A-R-Beta 2 or -Beta 1.
Target Information
Gamma-amino butyric acid (GABA) is a strong inhibitor of neuronal transmission and is found throughout the central nervous system. GABA is formed by the decarboxylation of glutamate, resulting in two distinct receptor types: GABA-A and GABA-B.
Binding of GABA to GABA-A receptors increases chloride ion transport into neurons, leading to signal repression. Insufficient GABA-mediated signaling can result in system overloads causing blackouts, rapid contractions, seizures, and epilepsy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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