Thermo Fisher Scientific GABRB3 Monoclonal Antibody (N87/25), FITC
GABRB3 단백질을 인식하는 FITC 결합 단일클론 항체로, WB, IHC, ICC/IF 등 다양한 응용에 적합합니다. 인간, 마우스, 랫트 반응성이 있으며 55kDa 단백질을 검출합니다. 단백질 G 정제, 액상 형태로 제공되며 4°C 암소 보관이 필요합니다.
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Thermo Fisher Scientific GABRB3 Monoclonal Antibody (N87/25), FITC
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Antibody Microarray (AM) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N87/25 |
| Immunogen | Fusion protein amino acids 370–433 of mouse GABA-A-R-Beta 3 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 9.1 mM sodium bicarbonate/PBS (pH 7.4) with 640.91 mM DMSO, 136.36 mM ethanolamine |
| Contains | No preservative |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931920 |
Product Specific Information
1 µg/mL of MA5-45466 was sufficient for detection of Beta 3 GABA receptor in 10 µg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
Detects approximately 55 kDa. No cross-reactivity against GABA-A-R-Beta 2 or Beta 1.
Target Information
Gamma-amino butyric acid (GABA) is a major inhibitory neurotransmitter found throughout the central nervous system.
GABA is formed by decarboxylation of glutamate and exists as two receptor types: GABA-A and GABA-B.
Binding of GABA to GABA-A receptors increases chloride ion influx into neurons, leading to signal repression.
Deficiency in GABA-mediated signaling can result in blackouts, rapid body contractions, seizures, and epilepsy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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