Thermo Fisher Scientific GABRB3 Monoclonal Antibody (N87/25), PerCP
GABRB3 단백질을 인식하는 마우스 단클론 항체로 PerCP 형광표지되어 있습니다. Western blot, IHC, ICC/IF 등 다양한 응용에 적합합니다. 인간, 마우스, 랫트 반응성이 있으며 고순도의 Protein G 정제 항체입니다.
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Thermo Fisher Scientific GABRB3 Monoclonal Antibody (N87/25), PerCP
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Antibody Microarray (AM) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N87/25 |
| Immunogen | Fusion protein amino acids 370–433 of mouse GABA-A-R-Beta 3 |
| Conjugate | PerCP |
| Excitation / Emission Max | 482 / 675 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931921 |
Available Formats
Product Specific Information
1 µg/mL of MA5-45467 was sufficient for detection of Beta 3 GABA receptor in 10 µg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 55 kDa. No cross-reactivity against GABA-A-R-Beta 2 or -Beta 1.
Target Information
Gamma-amino butyric acid (GABA) is a strong inhibitor of neuron transmission and is found throughout the central nervous system. GABA is formed by the decarboxylation of glutamate, resulting in the formation of two distinct types: GABA-A and GABA-B. The binding of GABA to GABA-A receptors increases chloride ion transport into neurons, repressing signal transmission. Insufficient GABA signaling can lead to blackouts, rapid body contractions, seizures, and epilepsy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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