Thermo Fisher Scientific INHA Monoclonal Antibody (4A2)
INHA 단백질을 표적하는 Mouse IgG1 단클론 항체로, IHC, ICC/IF, ELISA에 적합합니다. 인간 샘플에서 반응하며 약 40kDa INHA 단백질을 검출합니다. 연구용으로만 사용되며 장기 보관 시 -20°C에서 보관 권장.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4A2 |
| Immunogen | Purified recombinant fragment of human INHA expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10989129 |
Product Specific Information
MA5-15315 targets INHA (Inhibin alpha) in indirect ELISA, IF, and IHC applications and shows reactivity with human samples.
The immunogen is a purified recombinant fragment of human INHA expressed in E. coli.
MA5-15315 detects INHA (Inhibin alpha), which has a predicted molecular weight of approximately 40 kDa.
Target Information
The inhibin alpha subunit joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin negatively regulates gonadal stromal cell proliferation and exhibits tumor-suppressor activity.
Serum levels of inhibin reflect granulosa-cell tumor size and can serve as a marker for primary and recurrent disease.
In prostate cancer, inhibin alpha-subunit gene expression is suppressed and undetectable in poorly differentiated tumor cells.
Expression levels vary across gonadal and extragonadal tissues, suggesting that inhibin may function as both a growth/differentiation factor and a hormone.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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