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카탈로그 번호 | 설명 | 상태 | 단위 | 가격 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
634760 | Takara 634760 Embgenix™ PGT-A Kit (RUO), 96 Rxns pk | 재고문의 | pk | 12,193,000원 | 13,412,300원 |
The Embgenix PGT-A Kit (RUO) and accompanying analysis software provide a complete solution for next-generation sequencing (NGS)-based detection of chromosomal copy number variations (CNVs) from embryo biopsy samples. The kit enables accurate identification of whole chromosome, segmental, and mosaic aneuploidies, and yields Illumina-compatible sequencing libraries in a scalable format to support medium- to high-throughput applications.
The Embgenix PGT-A Kit (RUO) and accompanying analysis software provide a complete solution for next-generation sequencing (NGS)-based detection of chromosomal copy number variations (CNVs) from embryo biopsy samples. The kit enables accurate identification of whole chromosome, segmental, and mosaic aneuploidies, and yields Illumina-compatible sequencing libraries in a scalable format to support medium- to high-throughput applications.
The kit employs PicoPLEX technology for highly reproducible whole genome amplification (WGA) and a streamlined library prep methodology that minimizes hands-on time and the likelihood of sample processing errors. PicoPLEX WGA is a widely applied technology for CNV detection from single cells and low-input DNA, both in the context of reproductive health research and beyond. The entire library preparation workflow can be completed in a single tube in about two hours, yielding NGS libraries that are broadly compatible with Illumina sequencing platforms and allow for multiplexing of up to 96 samples per sequencing run.
After sequencing, cloud-based Embgenix Analysis Software (RUO) is used for data analysis and reporting. The software’s algorithm is designed to compute calculated copy numbers (CCNs) using bin counts against an internally configured reference for accurate determination of chromosomal CNVs. The software supports both automated and manual calling of whole chromosome, segmental, and mosaic CNVs, and data can be conveniently visualized in a chart or an idiogram plot. The software also provides a variety of data output options, including bulk download of results and generation of customizable PDF reports.
Overview
- Complete solution for NGS-based CNV detection, including WGA, library preparation, and bioinformatic analysis
- Reliable detection of CNVs from trophectoderm (TE) biopsy samples, including whole-chromosome and segmental gains/losses ≥10 Mb and mosaicisms ≥30%
- Powered by industry-leading PicoPLEX WGA technology, providing unparalleled reproducibility and coverage uniformity
- Scalable library prep workflow requires about two hours of hands-on time and allows for multiplexing of up to 96 samples
- Broad compatibility with Illumina sequencing platforms; validated protocols provided for MiSeq® and NextSeq® 500/550
- Intuitive, cloud-based analysis software provided for streamlined processing of sequencing data and reporting of results
More Information
Applications
- Detection of CNVs in gDNA and embryo samples
- Reproductive health research
Additional product information
Please see the product`s Certificate of Analysis for information about storage conditions, product components, and technical specifications. Please see the Product Components List to determine kit components. Certificates of Analysis and Product Components Lists are located under the Documents tab.
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