Thermo Fisher Scientific Human IL-2, Animal-Free Recombinant Protein, PeproTech
인간 IL-2 재조합 단백질로 동물 유래 성분 없이 생산됨. T세포 활성화와 증식 연구에 적합. 고순도(≥98%) 및 낮은 엔도톡신(<0.1 EU/µg). E. coli 발현 시스템 사용, 동결건조 형태로 제공.
- 카탈로그번호
- AF-200-02-xxx (5개 옵션)
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
5개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Human IL-2, Animal-Free Recombinant Protein, PeproTech
Applications
Functional Assay (Functional)
- Assay-dependent
In vitro Assay (IV)
- Refer to publications (115 available)
Miscellaneous PubMed (Misc)
- Refer to publications (7 available)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Published species | Bovine, Human, Mouse |
| Expression System | E. coli |
| Amino Acid Sequence | MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK ATELKHLQCL EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN RWITFAQSII STLT |
| Molecular Weight | 15.5 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥ 98% by SDS-PAGE gel and HPLC analyses |
| Endotoxin Concentration | < 0.1 EU/µg |
| Activity | ED50 ≤ 0.1 ng/ml (specific activity ≥ 1 × 10⁷ units/mg) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Purified |
| Contains | No preservative |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient |
Product Specific Information
Recombinant Human IL-2 is a 15.5 kDa protein containing 134 amino acid residues and one intrachain disulfide bond.
This product is shipped at ambient temperature. For storage, handling, and reconstitution information, please refer to the lot-specific Certificate of Analysis.
Target Information
Interleukin 2 (IL-2) is an immunomodulatory cytokine essential for:
- Proliferation of activated T cells
- Differentiation of B cells, NK cells, monocytes, and macrophages
IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric complex whose gamma chain is shared with IL-4 and IL-7.
In mature thymocytes, IL-2 gene expression is monoallelic, representing a unique regulatory mechanism.
Disruption of IL-2-like genes in mice results in colitis-like disease, highlighting its critical role in immune response regulation.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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