Thermo Fisher Scientific Human IL-3, Animal-Free Recombinant Protein, PeproTech
인간 IL-3 재조합 단백질로, E. coli에서 발현된 동물 유래 성분 없는 고순도 시약입니다. 인간 TF-1 세포 증식을 유도하는 생물활성이 높으며, 다양한 조혈세포 성장 및 분화 연구에 적합합니다. 연구용으로만 사용 가능합니다.
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Applications
Functional Assay (Functional)
- Assay-dependent
In vitro Assay (IV)
- Refer to publications (44)
Miscellaneous PubMed (Misc)
- Refer to publication (1)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Published Species | Human, Mouse |
| Expression System | E. coli |
| Amino Acid Sequence | APMTQTTSLK TSWVNCSNMI DEIITHLKQP PLPLLDFNNL NGEDQDILME NNLRRPNLEA FNRAVKSLQN ASAIESILKN LLPCLPLATA APTRHPIHIK DGDWNEFRRK LTFYLKTLEN AQAQQTTLSL AIF |
| Molecular Weight | 15 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥ 98% by SDS-PAGE gel and HPLC analyses |
| Endotoxin Concentration | <0.1 EU/µg |
| Activity | ED50 ≤ 0.1 ng/ml (specific activity ≥ 1 × 10⁷ units/mg) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Purified |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient |
Product Specific Information
Recombinant Human IL-3 is a 15.0 kDa globular protein containing 133 amino acid residues.
This product is shipped at ambient temperature.
For storage, handling, and reconstitution information, please see the lot-specific Certificate of Analysis.
Target Information
Interleukin 3 (IL-3), also known as Mast Cell Growth Factor (MCGF), Multi-Colony Stimulating Factor (multi-CSF), or Eosinophil-CSF (E-CSF), is produced by activated T cells, mast cells, and eosinophils.
IL-3 is a hematopoietic growth factor that stimulates colony formation of erythroid, megakaryocyte, neutrophil, eosinophil, basophil, mast cell, and monocytic lineages.
Its functions are often enhanced or dependent on co-stimulation with other cytokines.
Human and mouse IL-3 share only 29% sequence identity, and bioactivity is highly species-specific — human IL-3 has no activity on mouse cells.
IL-3 supports proliferation of a broad range of hematopoietic cell types and is involved in cell growth, differentiation, and apoptosis.
It also possesses neurotrophic activity and may be associated with neurologic disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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