Thermo Fisher Scientific Human IL-2, Animal-Free Recombinant Protein, PeproTech
인간 IL-2 재조합 단백질로 면역세포 활성화 연구에 사용됩니다. E. coli 발현 시스템에서 생산되며 ≥98%의 고순도 제품입니다. 동물 유래 성분이 없는 Animal-Free 포맷으로 제공됩니다. 세포 증식 활성 시험에서 높은 생물학적 활성을 보입니다.
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Applications
Functional Assay (Functional)
- Assay-dependent
In vitro Assay (IV)
- Refer to 115 publications
Miscellaneous PubMed (Misc)
- Refer to 7 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Published species | Bovine, Human, Mouse |
| Expression System | E. coli |
| Amino Acid Sequence | MAPTSSSTKK TQLQLEHLLL DLQMILNGIN NYKNPKLTRM LTFKFYMPKK ATELKHLQCL EEELKPLEEV LNLAQSKNFH LRPRDLISNI NVIVLELKGS ETTFMCEYAD ETATIVEFLN RWITFAQSII STLT |
| Molecular Weight | 15.5 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥ 98% by SDS-PAGE gel and HPLC analyses |
| Endotoxin Concentration | < 0.1 EU/µg |
| Activity | ED50 ≤ 0.1 ng/ml (specific activity ≥ 1 × 10⁷ units/mg) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Purified |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient |
Product Specific Information
Recombinant Human IL-2 is a 15.5 kDa protein containing 134 amino acid residues, including one intrachain disulfide bond.
This product is shipped at ambient temperature.
For storage, handling, and reconstitution information, please refer to the lot-specific Certificate of Analysis.
Target Information
Interleukin 2 (IL-2) is an immunomodulatory cytokine essential for the proliferation of activated T cells, and differentiation of B cells, natural killer cells, monocytes, and macrophages.
IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is shared by IL-4 and IL-7.
Expression of the IL-2 gene in mature thymocytes is monoallelic, representing a unique regulatory mechanism.
Disruption of an IL-2-like gene in mice leads to ulcerative colitis-like disease, indicating its critical role in immune response regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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