Thermo Fisher Scientific ICAM3 Monoclonal Antibody (OTI1F4), TrueMAB
인간 ICAM3 단백질을 인식하는 Mouse IgG2b 단일클론 항체로, Western blot에 적합합니다. 동결건조 형태이며 PBS 버퍼에 8% 트레할로스 포함. 연구용으로 세포 간 접착 및 면역 반응 연구에 활용 가능합니다.
- 카탈로그번호
- CF507143
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:400–1:4,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F4 |
| Immunogen | Full length human recombinant protein of human ICAM3 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
CD50 (ICAM-3) is a transmembrane glycoprotein expressed by leukocytes, acting as a counter-receptor for LFA-1 integrin. It mediates adhesion between T cells and antigen-presenting cells, regulates LFA-1 affinity for ICAM-1, and induces T cell activation and proliferation.
ICAM-3 is crucial for initiating immune responses in both T cells and antigen-presenting cells and interacts with CD209 (DC-SIGN), facilitating communication between dendritic cells and granulocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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