Thermo Fisher Scientific MBL2 Monoclonal Antibody (OTI1A12), TrueMAB
MBL2 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot, IHC, ICC에 적합합니다. 동결건조 형태로 제공되며, 1 mg/mL 농도로 재구성 가능합니다. 인간 시료에 반응하며, 친화 크로마토그래피로 정제되었습니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A12 |
| Immunogen | Full length human recombinant protein of human MBL2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
MBL2 is a calcium-dependent lectin involved in innate immune defense. It binds mannose, fucose, and N-acetylglucosamine on various microorganisms, activating the lectin complement pathway.
Additionally, MBL2 binds to late apoptotic and necrotic cells, facilitating their clearance by macrophages, but not to early apoptotic cells. It may also bind DNA.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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