Thermo Fisher Scientific DNMT2 Polyclonal Antibody
DNMT2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Western blot과 ELISA에 적합합니다. 고순도 친화 크로마토그래피 정제, PBS/glycerol buffer 포뮬레이션, -20°C 보관. 연구용 전용 제품입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 192–391 of human TRDMT1 (NP_0044031) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.64 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804546 |
Product Specific Information
Immunogen sequence:
VHPQKYAMDV ENKIQEKNVE PNISFDGSIQ CSGKDAILFK LETAEEIHRK NQQDSDLSVK MLKDFLEDDT DVNQYLLPPK SLLRYALLLD IVQPTCRRSV CFTKGYGSYI EGTGSVLQTA EDVQVENIYK SLTNLSQEEQ ITKLLILKLR YFTPKEIANL LGFPPEFGFP EKITVKQRYR LLGNSLNVHV VAKLIKILYE
Positive Samples: SKOV3, 293T, DU145, HeLa, H460
Cellular Location: Nucleus
Target Information
CpG methylation is an epigenetic modification important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have shown that DNA methylation is required for mammalian development. This gene encodes a protein similar to DNA methyltransferases but lacking methyltransferase activity. The protein binds strongly to DNA, suggesting it may mark specific genomic sequences. Alternative splicing results in multiple transcript variants encoding different isoforms.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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