Thermo Fisher Scientific BCKDHB Polyclonal Antibody
Thermo Fisher Scientific의 BCKDHB Polyclonal Antibody는 Mouse 및 Rat 시료에서 Western blot과 ELISA에 적합합니다. Rabbit IgG 기반의 비결합 항체로, 고순도 친화 크로마토그래피로 정제되었습니다. BCKDHB 단백질 연구 및 미토콘드리아 관련 대사 연구에 유용합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 183–392 of human BCKDHB (NP_8988711) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.7 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804545 |
Product Specific Information
- Immunogen sequence:
RSPWGCVGHG ALYHSQSPEA FFAHCPGIKV VIPRSPFQAK GLLLSCIEDK NPCIFFEPKI LYRAAAEEVP IEPYNIPLSQ AEVIQEGSDV TLVAWGTQVH VIREVASMAK EKLGVSCEVI DLRTIIPWDV DTICKSVIKT GRLLISHEAP LTGGFASEIS STVQEECFLN LEAPISRVCG YDTPFPHIFE PFYIPDKWKC YDALRKMINY - Positive Samples: Mouse pancreas
- Cellular Location: Mitochondrion matrix
Target Information
Branched-chain keto acid dehydrogenase is a multienzyme complex associated with the inner membrane of mitochondria and functions in the catabolism of branched-chain amino acids. The complex consists of multiple copies of three components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2), and lipoamide dehydrogenase (E3).
This gene encodes the E1 beta subunit, and mutations therein have been associated with maple syrup urine disease (MSUD), type 1B — characterized by a maple syrup odor in the urine, mental and physical retardation, and feeding problems.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(PA5-87963_BCKDHB_P21953-1_Rabbit.svg 및 PA5-87963_BCKDHB_P21953-1_Rabbit_PDP.jpeg)
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