Thermo Fisher Scientific BCKDHB Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:5,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 183-392 of human BCKDHB (NP_8988711) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:BCKDHB,uniProtId:P21953-1,ncbiNodeId:9606,antigenRange:183-392,antigenLength:392,antigenImageFileName:PA5-87963_BCKDHB_P21953-1_Rabbit.svg,antigenImageFileNamePDP:PA5-87963_BCKDHB_P21953-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.7 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804545

Product Specific Information

Immunogen sequence: RSPWGCVGHG ALYHSQSPEA FFAHCPGIKV VIPRSPFQAK GLLLSCIEDK NPCIFFEPKI LYRAAAEEVP IEPYNIPLSQ AEVIQEGSDV TLVAWGTQVH VIREVASMAK EKLGVSCEVI DLRTIIPWDV DTICKSVIKT GRLLISHEAP LTGGFASEIS STVQEECFLN LEAPISRVCG YDTPFPHIFE PFYIPDKWKC YDALRKMINY; Positive Samples: Mouse pancreas; Cellular Location: Mitochondrion matrix

Target Information

Branched-chain keto acid dehydrogenase is a multienzyme complex associated with the inner membrane of mitochondria, and functions in the catabolism of branched-chain amino acids. The complex consists of multiple copies of 3 components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). This gene encodes the E1 beta subunit, and mutations therein have been associated with maple syrup urine disease (MSUD), type 1B, a disease characterized by a maple syrup odor to the urine in addition to mental and physical retardation, and feeding problems.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.