Thermo Fisher Scientific Cytochrome C Monoclonal Antibody (6H2.B4), Alexa Fluor 488
Alexa Fluor 488로 표지된 Cytochrome C 단클론 항체로, 인간, 마우스, 랫 등 다양한 종에 반응합니다. 세포면역염색 및 유세포분석에 적합하며, 단백질 A로 정제된 고순도 항체입니다. 4°C에서 암소 보관하며 동결 금지.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunocytochemistry (ICC/IF) | 1–10 µg/mL | - |
| Flow Cytometry (Flow) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Fruit fly, Human, Mouse, Rabbit, Rat |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6H2.B4 |
| Immunogen | Rat cytochrome C |
| Conjugate | Alexa Fluor™ 488 |
| Excitation / Emission Max | 499 / 520 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE! |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2663051 |
Additional Formats
Product Specific Information
This antibody reacts with native Cytochrome C but does not recognize denatured Cytochrome C.
It recognizes a region in the vicinity of amino acid 62 of rat Cytochrome C.
Target Information
Cytochrome C is an electron-transporting protein located in the mitochondrial intermembrane space, essential for oxidative phosphorylation and ATP production.
Upon apoptotic stimuli, cytochrome C is released into the cytosol, where it binds apoptotic protease activating factor and activates procaspase 9.
Cytosolic cytochrome C subsequently activates caspase 3, a key effector in apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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