Thermo Fisher Scientific Lamin B2 Monoclonal Antibody (E-3), Alexa Fluor 555
Alexa Fluor 555로 결합된 Lamin B2 단클론 항체로, 인간·생쥐·닭·쥐 시료에 반응합니다. 면역세포염색(ICC/IF)에 적합하며, 단백질 A로 정제된 고순도 액상 형태입니다. 4°C 암저장, 동결 금지 조건에서 안정적으로 보관 가능합니다.
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Applications
- Immunocytochemistry (ICC/IF)
- Tested Dilution: 1–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chicken, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | E-3 |
| Immunogen | Extracts from chicken nuclei |
| Conjugate | Alexa Fluor™ 555 |
| Excitation / Emission Max | 553 / 568 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2662665 |
Additional Formats
- Unconjugated ([33-2100])
- Alexa Fluor 488 ([MA3-32100-A488])
- Alexa Fluor 647 ([MA3-32100-A647])
- Request custom conjugation
Target Information
Nuclear lamins form a network of intermediate-type filaments at the nucleoplasmic site of the nuclear membrane. Two main subtypes of nuclear lamins are distinguished: A-type lamins and B-type lamins.
A-type lamins (lamin A, lamin C, lamin Adel 10) arise from the same gene by alternative splicing, while B-type lamins (lamin B1 and lamin B2) derive from two distinct genes.
Mutations in A-type lamins are associated with rare dominant genetic disorders such as Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy with conduction-system disease, and Dunnigan-type familial partial lipodystrophy.
A-type lamins interact with chromatin and are implicated in regulating differential gene expression during cell differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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