Thermo Fisher Scientific NR1I3 Monoclonal Antibody (OTI1C6), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:150

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

This gene encodes a member of the nuclear receptor superfamily and is a key regulator of xenobiotic and endobiotic metabolism.
The protein binds DNA as a monomer or heterodimer with the retinoid X receptor and regulates transcription of genes involved in drug metabolism and bilirubin clearance, such as cytochrome P450 family members.
Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.