Thermo Fisher Scientific NR1I3 Monoclonal Antibody (OTI10B1), TrueMAB

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:150

Product Specifications

Product Specific Information

• For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
• For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).

Target Information

This gene encodes a member of the nuclear receptor superfamily and is a key regulator of xenobiotic and endobiotic metabolism.
The protein binds to DNA as a monomer or as a heterodimer with the retinoid X receptor, regulating transcription of genes involved in drug metabolism and bilirubin clearance (e.g., cytochrome P450 family members).
Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but can be modulated by agonists and inverse agonists.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.