Thermo Fisher Scientific GIRK1 (Kir3.1) Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:200

Product Specifications

Product Specific Information

• Reconstitution: 25 µL, 50 µL, or 0.2 mL double distilled water (DDW), depending on sample size.
• The antibody ships as a lyophilized powder at room temperature.
• Upon arrival, store at -20°C.
• The reconstituted solution can be stored at 4°C, protected from light, for up to 1 week.
• For longer storage, aliquot and keep at -20°C.
• Avoid multiple freeze/thaw cycles.
• Centrifuge all antibody preparations before use (10,000 × g, 5 min).

Target Information

This potassium channel is controlled by G proteins. Inward rectifier potassium channels preferentially allow potassium influx rather than efflux. Their voltage dependence is modulated by extracellular potassium concentration; as external potassium increases, the voltage range for channel opening shifts to more positive potentials. The inward rectification arises mainly from blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.