Thermo Fisher Scientific PARP1 (cleaved Asp214) Recombinant Rabbit Monoclonal Antibody (PARP-H8)
PARP1 (cleaved Asp214) 인식하는 재조합 토끼 단클론 항체로, Western blot과 유세포분석(Flow Cytometry)에 적합합니다. 인간 시료 반응성이 있으며, HEK293 세포에서 발현된 IgG1, kappa 형 항체입니다. 단백질 A/G로 정제되었으며, -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Assay-dependent
Flow Cytometry (Flow)
- 1–1,000 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PARP-H8 |
| Immunogen | A synthetic peptide corresponding to residues surrounding Asp214 of human PARP. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 50% glycerol, 0.2% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897046 |
Additional Formats
Target Information
Poly ADP-Ribose Polymerase (PARP) uses nicotinamide adenine dinucleotide (oxidized form) NAD as a substrate to catalyze the transfer of ADP-ribose to a variety of nuclear protein acceptors. Proteolysis of PARP to its stable 85 kDa fragment is an early marker of programmed cell death (apoptosis) and is mediated by the caspase CPP32 protein. Cleavage occurs between Asp216 and Gly217, a site in PARP conserved across species.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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