Thermo Fisher Scientific PARP1 (cleaved Asp214) Recombinant Rabbit Monoclonal Antibody (PARP-H8), PE
인간 PARP1 (cleaved Asp214)에 특이적인 재조합 토끼 단클론 항체로, PE 형광체가 결합된 형광유세포분석용 항체입니다. HEK293 발현 시스템에서 생산되었으며, Protein A/G로 정제되었습니다. 세포사멸 마커 연구 및 PARP 활성 분석에 적합합니다.
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Thermo Fisher Scientific PARP1 (cleaved Asp214) Recombinant Rabbit Monoclonal Antibody (PARP-H8), PE
Applications
- Flow Cytometry (Flow)
Tested Dilution: 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PARP-H8 |
| Immunogen | A synthetic peptide corresponding to residues surrounding Asp214 of human PARP |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897047 |
Additional Formats
Target Information
Poly ADP-Ribose Polymerase (PARP) uses nicotinamide adenine dinucleotide (NAD) as a substrate to catalyze the transfer of ADP-ribose to various nuclear protein acceptors. Proteolysis of PARP to its stable 85 kDa fragment is an early marker of apoptosis and is mediated by caspase CPP32. Cleavage occurs between Asp216 and Gly217, a conserved site across species.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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