Thermo Fisher Scientific PARP1 (cleaved Asp214) Recombinant Rabbit Monoclonal Antibody (PARP-H8), FITC
PARP1 (cleaved Asp214) 표적에 특이적인 FITC 결합 재조합 토끼 단클론 항체. Flow Cytometry에 적합하며 인간 시료 반응성. 고순도 Protein A/G 정제, 4°C 암소 보관. 연구용 전용 시약.
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Thermo Fisher Scientific PARP1 (cleaved Asp214) Recombinant Rabbit Monoclonal Antibody (PARP-H8), FITC
Applications
- Flow Cytometry (Flow)
Tested Dilution: 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PARP-H8 |
| Immunogen | Synthetic peptide corresponding to residues surrounding Asp214 of human PARP |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897048 |
Additional Formats
- Unconjugated (MA5-37112)
- APC (MA5-37115)
- PE (MA5-37113)
- Custom conjugation available upon request
Target Information
Poly ADP-Ribose Polymerase (PARP) uses NAD (oxidized form) as a substrate to catalyze the transfer of ADP-ribose to various nuclear protein acceptors. Proteolysis of PARP to its stable 85 kDa fragment is an early marker of apoptosis and is mediated by caspase CPP32. Cleavage occurs between Asp216 and Gly217, a site conserved across species.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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