Thermo Fisher Scientific MRP1 Monoclonal Antibody (IU2H10)
MRP1 단백질을 인식하는 Mouse monoclonal antibody (Clone IU2H10). Western blot, IHC, ICC/IF, Flow cytometry 등 다양한 응용에 사용 가능. Human, Mouse, Rat 반응성. 단백질 G로 정제된 액상 형태, 1 mg/mL 농도.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500 | - |
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-Dependent | - |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | - |
| Flow Cytometry (Flow) | Assay-Dependent | - |
| ELISA | Assay-Dependent | - |
| Immunoprecipitation (IP) | Assay-Dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | IU2H10 |
| Immunogen | Recombinant peptide (a.a. 1–33) of human MRP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C or −80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11157261 |
Target Information
The protein encoded by this gene belongs to the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes.
ABC genes are divided into seven subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
This transporter is part of the MRP subfamily involved in multidrug resistance and functions as a multispecific organic anion transporter. Substrates include oxidized glutathione, cysteinyl leukotrienes, and activated aflatoxin B1, as well as glucuronides and sulfate conjugates of steroid hormones and bile salts.
Alternative splicing results in several variants, all maintaining the original open reading frame.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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