Thermo Fisher Scientific GABRB3 Monoclonal Antibody (N87/25), APC
GABRB3 단백질을 인식하는 마우스 단클론 항체로, APC 형광 표지되어 있습니다. Western blot, IHC, ICC/IF 등 다양한 응용에 적합합니다. 사람, 마우스, 랫트 반응성이 있으며, 단백질 G로 정제된 액상 형태입니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- MA545465
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Antibody Microarray (AM) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N87/25 |
| Immunogen | Fusion protein amino acids 370–433 of mouse GABA-A-R-Beta 3 |
| Conjugate | APC (Allophycocyanin) |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.46 mM phosphate / 2.48 mM MES, pH 7.4, with 2 mM EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931919 |
Additional Formats
- Unconjugated (Cat. MA5-27698)
- FITC (Cat. MA5-45466)
- PE (Cat. MA5-45468)
- PerCP (Cat. MA5-45467)
- Custom conjugation available upon request
Product Specific Information
1 µg/mL of MA5-45465 was sufficient for detection of Beta 3 GABA receptor in 10 µg of rat brain lysate by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 55 kDa. No cross-reactivity against GABA-A-R-Beta 2 or -Beta1.
Target Information
Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter found throughout the central nervous system. It is formed by the decarboxylation of glutamate and acts through GABA-A and GABA-B receptor types. Binding of GABA to GABA-A receptors increases chloride ion influx, leading to inhibition of neuronal firing. Dysregulation of GABA signaling can cause seizures, blackouts, and epilepsy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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