Thermo Fisher Scientific CDK15 Monoclonal Antibody (OTI4H2)

Applications

• Western Blot (WB): 1:500

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).

Target Information

Protein kinases are enzymes that transfer phosphate groups from donors (typically the γ-phosphate of ATP) to specific amino acids in substrate proteins. Through this mechanism, they regulate a wide range of cellular processes including metabolism, transcription, cell cycle progression, cytoskeletal dynamics, apoptosis, and differentiation.
The protein kinase family, encompassing over 500 gene products, is one of the largest in eukaryotes and is divided into eight major groups based on catalytic domain sequences.
The STE group (homologs of yeast Sterile 7, 11, 20 kinases) includes about 50 kinases associated with the mitogen-activated protein kinase (MAPK) cascade. These cascades, comprising MAPK and upstream kinases (MAPKKs), are well characterized in the yeast pheromone response pathway, where pheromone binding triggers MAPK pathway activation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.