Thermo Fisher Scientific UBA3 Monoclonal Antibody (OTI3F9), TrueMAB
UBA3 단백질 인식용 mouse monoclonal 항체로 Western blot에 최적화됨. Human, Mouse, Rat 등 다양한 종에 반응. Lyophilized 형태로 제공되며, 재구성 후 1 mg/mL 농도 유지. 연구용 단백질 유비퀴틴화 관련 실험에 적합.
- 카탈로그번호
- CF811882
- 판매단위
- pk
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3F9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–463 of human UBA3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
UBA3 is part of the ubiquitin-activating enzyme (E1) family, crucial for protein ubiquitination—a process targeting abnormal or short-lived proteins for degradation.
UBA3 associates with AppBp1 to form a heterodimer complex that activates NEDD8, a ubiquitin-like protein involved in cell division, signaling, and embryogenesis.
Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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