Thermo Fisher Scientific UBA3 Monoclonal Antibody (OTI1B10), TrueMAB

Applications

• Western Blot (WB): 1:500 dilution tested

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

UBA3 is a member of the E1 ubiquitin-activating enzyme family. It forms a heterodimer with AppBp1 (amyloid beta precursor protein binding protein) and activates NEDD8, a ubiquitin-like protein involved in cell division, signaling, and embryogenesis.
This process is essential for ubiquitin-mediated protein degradation, targeting abnormal or short-lived proteins. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.