Thermo Fisher Scientific UBA3 Monoclonal Antibody (OTI1B10), TrueMAB
UBA3 단백질을 인식하는 Mouse monoclonal 항체로 Western blot에 적합합니다. Human, Mouse, Rat 등 다양한 종에 반응하며, Lyophilized 형태로 제공됩니다. PBS buffer에 trehalose가 포함되어 안정성이 높습니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:500 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–463 of human UBA3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
UBA3 is a member of the E1 ubiquitin-activating enzyme family. It forms a heterodimer with AppBp1 (amyloid beta precursor protein binding protein) and activates NEDD8, a ubiquitin-like protein involved in cell division, signaling, and embryogenesis.
This process is essential for ubiquitin-mediated protein degradation, targeting abnormal or short-lived proteins. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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