Thermo Fisher Scientific IL-19 Monoclonal Antibody (RN19), eBioscience
마우스 IL-19 단백질을 인식하는 단클론 항체로, ELISA 캡처용으로 검증됨. Rat IgG1, kappa 아이소타입이며, 비접합 형태로 제공. 친화 크로마토그래피로 정제되어 0.5 mg/mL 농도로 PBS(pH 7.2)에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| ELISA | 1–4 µg/mL | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Rat / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | RN19 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1234935 |
Product Specific Information
Description:
The RN19 antibody reacts with mouse interleukin-19 (IL-19), a member of the IL-10 family, which is secreted by activated keratinocytes and monocytes.
Applications Reported:
The RN19 antibody has been reported for use in ELISA capture of mouse IL-19.
Applications Tested:
The RN19 antibody has been tested as the capture antibody in a sandwich ELISA for analysis of mouse IL-19 in combination with a biotinylated polyclonal anti-mouse IL-19 antibody for detection.
A suitable concentration range for ELISA capture is 1.0–4 µg/mL.
A standard curve with doubling dilutions of recombinant standard from 4000 pg/mL to 30 pg/mL should be included in each ELISA plate.
Purity: Greater than 90%, as determined by SDS-PAGE.
Aggregation: Less than 10%, as determined by HPLC.
Filtration: 0.2 µm post-manufacturing filtered.
Target Information
The protein encoded by this gene is a cytokine belonging to the IL-10 cytokine subfamily. It is preferentially expressed in monocytes and binds the IL20 receptor complex, activating STAT3. In mouse, it up-regulates IL6 and TNF-alpha expression and induces apoptosis, indicating a role in inflammatory responses. Alternatively spliced transcript variants encoding distinct isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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