Thermo Fisher Scientific IGSF8 Polyclonal Antibody

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 15 µg/mL

Product Specifications

Product Specific Information

• Percent identity with other species by BLAST analysis:
  Human, Gorilla, Gibbon, Monkey, Marmoset, Bovine, Bat, Elephant, Panda, Rabbit, Pig (100%); Mouse, Rat (93%)
• Immunohistochemistry with formalin-fixed paraffin-embedded tissues requires pretreatment using HIER with citrate buffer.

Target Information

This gene encodes a member of the EWI subfamily of the immunoglobulin protein superfamily.
Members of this family contain:

• A single transmembrane domain
• An EWI (Glu-Trp-Ile) motif
• A variable number of immunoglobulin domains

This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in cellular functions such as cell migration and viral infection.
It may also act as a tumor suppressor by inhibiting proliferation of certain cancers.
Alternate splicing results in multiple transcript variants that encode the same protein.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.