
Thermo Fisher Scientific ITGA3 Polyclonal Antibody
Rabbit polyclonal antibody against human ITGA3 (CD49c) for IHC-P applications. Reacts with human and bovine samples. Antigen affinity purified, 1 mg/mL in PBS with 0.1% sodium azide. Suitable for research use only.
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- PA532881
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- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested dilution: 7.5–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from N-terminus of human ITGA3 / CD49c |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550342 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gorilla, Monkey, Bovine: 100%
- Marmoset, Mouse, Dog, Bat, Hamster, Elephant, Horse, Opossum: 94%
- Rabbit: 89%
Target Information
ITGA3 (Integrin, Alpha-3), also known as CD49c, VLA3, or GAPB3, is a cell surface adhesion molecule encoded by the ITGA3 gene located on chromosome 17q21.33.
ITGA3 forms part of the alpha3beta1 integrin complex, which plays a key role in neural migration and corticogenesis through interaction with the beta-1 subunit.
It has been linked to DAB1 phosphorylation signaling, influencing neuronal detachment from radial glial fibers.
Expression of human ITGA3 enhances viral infectivity in Chinese hamster ovary cells.
The protein includes 13 potential N-glycosylation sites, 2 cleavage sites, and 7 N-terminal repeating units typical of integrins.
Recombinant ITGA3 is expressed as a 150-kDa protein, consistent with the native form observed by western blot.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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