Thermo Fisher Scientific INPP5J Polyclonal Antibody
Human INPP5J 단백질을 인식하는 Rabbit Polyclonal Antibody. IHC(P)에서 검증되었으며, 항원 친화 크로마토그래피로 정제됨. PBS buffer에 0.1% sodium azide 포함, 1 mg/mL 농도. 연구용으로만 사용 가능.
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- PA532876
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- pk
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Applications
Immunohistochemistry (Paraffin) [IHC (P)]
- Tested Dilution: 10–15 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 15 amino acid peptide from N-terminus of human INPP5J / PIB5PA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550337 |
Product Specific Information
- Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Gibbon (87%); Marmoset (80%)
- For IHC(P), use heat-induced antigen retrieval in pH 6.0 citrate buffer.
- After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
Target Information
Inositol and phosphatidylinositol phosphates are important for numerous cellular processes, including neuronal survival and signal transduction from growth factors, neurotransmitters, and G protein-coupled receptors.
INPP5J (inositol polyphosphate-5-phosphatase J), also known as phosphatidylinositol 4,5-bisphosphate 5-phosphatase A, PIPP, PIB5PA, or INPP5, is a 1,006 amino acid cytoplasmic protein that assists in the conversion of inositol 1,4-bisphosphate from inositol 1,4,5-trisphosphate.
Expressed in lung, stomach, kidney, brain, small intestine, and heart, INPP5J localizes to membrane ruffles, where it may participate in modulating inositol and phosphatidylinositol polyphosphate-binding proteins.
Encoded by a gene located on human chromosome 22, INPP5J undergoes alternative splicing to produce three isoforms.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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