Thermo Fisher Scientific Phospho-MAP2K4 (Ser257) Recombinant Rabbit Monoclonal Antibody (SEK1MKK4S257-C5), PE
Phospho-MAP2K4 (Ser257)을 인식하는 재조합 토끼 단클론 항체로, PE 형광 표지되어 Flow Cytometry에 적합합니다. 인간, 마우스, 비인간 영장류에 반응하며, Protein A/G로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
- Flow Cytometry (Flow): 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SEK1MKK4S257-C5 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser257 of human phospho SEK1/MKK4 |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897072 |
Additional Formats
- Unconjugated (Cat. MA5-37137)
- APC (Cat. MA5-37140)
- FITC (Cat. MA5-37139)
- Custom conjugation available upon request
Target Information
MAP2K4 (MEK4) is a serine/threonine kinase of the STE7 family that phosphorylates and activates JNK1, JNK2, and p38. It preferentially phosphorylates tyrosine residues of JNKs and mediates cellular stress and inflammatory responses. MAP2K4 plays roles in carcinogenesis; loss-of-function mutations have been identified in lung and pancreatic tumors, while pro-oncogenic activity has also been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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