Thermo Fisher Scientific BCL11A Recombinant Rabbit Monoclonal Antibody (ARC1486)
BCL11A 단백질을 인식하는 재조합 토끼 단클론 항체로, WB 및 IHC(P) 실험에 적합합니다. 인간 시료 반응성이 있으며, HEK293 세포에서 발현된 IgG 형태입니다. 높은 순도(Protein A 정제)와 안정적인 액상 포맷으로 연구용에 최적화되어 있습니다.
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Applications
- Western Blot (WB): 1:500–1:1,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1486 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 401–589 of human CTIP1/BCL11A (Q9H165) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849683 |
Product Specific Information
Immunogen sequence:
GEKPYKCNLC DHACTQASKL KRHMKTHMHK SSPMTVKSDD GLSTASSPEP GTSDLVGSAS SALKSVVAKF KSENDPNLIP ENGDEEEEED DEEEEEEEEE EEEELTESER VDYGFGLSLE AARHHENSSR GAVVGVGDES RALPDVMQGM VLSSMQHFSE AFHQVLGEKH KRGHLAEAEG HRDTCDEDS
Target Information
This gene encodes a C2H2-type zinc-finger protein similar to mouse Bcl11a/Evi9. The mouse gene is a common site of retroviral integration in myeloid leukemia and may function as a leukemia disease gene through interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated and may be involved in lymphoma pathogenesis since translocations associated with B-cell malignancies deregulate its expression. Multiple transcript variants encoding several isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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