Thermo Fisher Scientific PRDX4 Polyclonal Antibody
PRDX4 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(P)에서 높은 특이성과 재현성 제공. 인간 및 마우스 반응성 확인됨. 항원 친화 크로마토그래피로 정제된 고품질 연구용 항체.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
- Publications: View 1 publication
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:1,000
- Publications: View reference
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment (AA 25–216, Q13162) of peroxiredoxin 4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.95 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C and avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2552205 |
Product Specific Information
- Recommended positive controls: NT2D1, mouse brain
- Predicted reactivity: Mouse (96%), Rat (96%), Zebrafish (88%), Xenopus laevis (94%), Rhesus Monkey (100%), Bovine (95%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Peroxiredoxin (Prx) is a peroxidase family associated with cell proliferation, differentiation, and apoptosis. Mammalian Prx consists of six members classified into typical 2-Cys, atypical 2-Cys, and 1-Cys Prx subgroups.
- Prx VI: 1-Cys subgroup
- Prx I, II, VI: Cytosol localization
- Prx III: Mitochondria
- Prx IV: Endoplasmic reticulum and secretion
- Prx V: Peroxisome, mitochondria, and cytosol
Mammalian Prxs are 20–30 kDa in size and exhibit thioredoxin-dependent peroxidase activity using thioredoxin, thioredoxin reductase, and NADPH as reducing systems.
⚠ WARNING
This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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