Thermo Fisher Scientific CHOP Polyclonal Antibody
CHOP 단백질 검출용 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot에 최적화되어 있으며, 다양한 종에서 높은 반응성. 액상 형태로 제공되며 4°C 또는 -20°C에서 안정적으로 보관 가능. 연구용으로만 사용.
- 카탈로그번호
- PA534848
- 판매단위
- pk
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Thermo Fisher Scientific CHOP Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:3,000
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 43–136 of GADD153 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.92 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2552200 |
Product Specific Information
- Recommended positive controls: HeLa (4 µg/mL, TM 12 hr)
- Predicted reactivity: Rat (100%), Rhesus Monkey (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
GADD153 is a small nuclear protein that can dimerize with transcription factors C/EBP alpha and beta. Once dimerized, this complex inhibits normal C/EBP binding and function at classical sites. Conversely, the C/EBP–GADD153 dimer gains binding activity to non-classical, stress-related targets.
Under normal conditions, GADD153 expression is undetectable but is strongly upregulated during cellular or ER stress, such as treatment with tunicamycin, nutrient starvation, or reducing agents affecting calcium flux across the ER membrane.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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