
Thermo Fisher Scientific KRT16 Monoclonal Antibody (OTI1G1), TrueMAB
KRT16 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 IHC(P) 실험에 적합. Human 및 Rat 시료에 반응하며, 동결건조 형태로 제공. 구조적 안정성 연구 및 각질세포 관련 질환 연구에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G1 |
| Immunogen | Full length human recombinant protein of human KRT16 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
KRT16 is a member of the keratin gene family, which encodes intermediate filament proteins maintaining the structural integrity of epithelial cells.
Type I cytokeratins are acidic proteins typically paired with type II keratins and are located on chromosome 17q12–q21.
KRT16 is coexpressed with keratin 14 in epithelial tissues such as the esophagus, tongue, and hair follicles.
Mutations in this gene are linked to type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma, and unilateral palmoplantar verrucous nevus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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