Thermo Fisher Scientific ATP6V1C2 Monoclonal Antibody (OTI8E2), TrueMAB
ATP6V1C2 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot에 최적화되어 있습니다. Human, Mouse, Rat에 반응하며, IgG1 아이소타입입니다. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능합니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8E2 |
| Immunogen | Full length human recombinant protein of human ATP6V1C2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
ATP6V1C2 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme responsible for acidifying eukaryotic intracellular organelles.
V-ATPase-dependent acidification is essential for:
- Protein sorting
- Zymogen activation
- Receptor-mediated endocytosis
- Synaptic vesicle proton gradient generation
The V-ATPase complex includes a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain contains ATP catalytic sites and multiple subunits (A, B, G, C, D, E, F, H).
Alternative splicing of ATP6V1C2 produces different isoforms of the V1 domain C subunit.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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