Thermo Fisher Scientific FDPS Polyclonal Antibody
FDPS 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot에 적합하며 Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제된 고순도 항체로, 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full-length Human FDPS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720540 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
The isoprene biosynthetic pathway supplies the cell with cholesterol, ubiquinone, and various nonsterol metabolites. Farnesylpyrophosphate synthetase (FDPS) catalyzes the formation of geranyl and farnesylpyrophosphate from isopentenylpyrophosphate and dimethylallyl pyrophosphate.
Studies in rat liver using immunofluorescence and immunoelectron microscopy demonstrated that FDPS is predominantly localized in peroxisomes.
Liver tissue from patients with peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy exhibit diminished FDPS activity and subsequent isoprenoid synthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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