Thermo Fisher Scientific NR5A2 Polyclonal Antibody
NR5A2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 다클론 항체로, Western blot, IHC, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 고순도(>95%)를 보유합니다. 인간, 마우스, 랫트 반응성으로 연구용에 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human NR5A2 (amino acids 1–541) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C (short term). For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2720546 |
Product Specific Information
This antibody was affinity-purified from rabbit antiserum using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
NR5A2 binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II region of hepatitis B virus genes, a critical cis-element for expression and regulation. It may be responsible for liver-specific enhancer II activity, likely in combination with other hepatocyte transcription factors. NR5A2 is a key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in the liver and may also contribute to the regulation of pancreas-specific genes and embryonic development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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