
Thermo Fisher Scientific SMARCB1 Polyclonal Antibody
SMARCB1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot, IHC, ICC, IP 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 고순도(>95%)를 보장합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Immunoprecipitation (IP) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full-length Human SMARCB1 (amino acids 1–385, UniProt ID: Q12824-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720547 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
The SWI-SNF complex is involved in transcriptional activation through ATP-dependent remodeling of nucleosome structure. Brm (SNF2α) and Brg-1 (SNF2β) are the ATPase subunits of the mammalian SWI-SNF complex. Core components include Brm, Brg-1, Ini1 (SNF5), BAF155 (SRG3), and BAF170, which together enhance chromatin remodeling activity. Additional subunits such as hSNF2L and hSNF2H are homologs of Drosophila ISWI and function in related chromatin remodeling complexes like NURF.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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